Calluses can become a big problem for weightlifters, which is caused by not wearing gloves when you're lifting weights. The friction between the hand and the bar caused by the movement and weight is the factor for getting a callus. Easy way to remove them is using a product called Calluses and scab remover. Apply liberally to spots making sure not to miss any spots. Allow to sit for one to two days and then presto you should see that your calluses have regressed or disappeared completely.